Efficacy and safety of inhalation 6% N-acetylcysteine in 3% NaCl solution in clinical practice (literature review)

The article summarizes the literature on use of N-acetylcysteine and its combination with 3% NaCl solution (FLU-ACYL broncho) in clinical practice. Studies show that is currently effective treatment respiratory diseases due to multicomponent effects system immune system. Hypertonic (3%) potentiates action by inhalation allows achieve good results acute chronic optimal time. One well-known Ukraine products for fast evacuation viscous sputum FLU-ACIL broncho, sterile nebulizer instillation. 5 ml ampoule contains 300 mg NAC, which has a mucolytic effect direct contact mucus, 150 hypertonic solution, draws water from intracellular space into extracellular osmosis increases proportion bronchial secretion, dilutes it thus facilitates removal. NAC creates synergy obtain minimal side effects. This mucolytic, anti-film, antiviral, antioxidant, anti-inflammatory immunomodulatory effects, making promising pandemic SARS-CoV-2. No conflict interests was declared authors.